miR-23a/b suppress cGAS-mediated innate and autoimmunity

Cyclic GMP-AMP synthase (cGAS), a key sensor of intracellular DNA, is essential for eliciting innate immunity against infection, whereas aberrant activation of cGAS by endogenous DNA promotes severe autoimmune diseases. However, it is largely unknown how cGAS expression is regulated during pathogen...

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Detalles Bibliográficos
Autores principales: Yu, Qiuya, Chu, Lei, Li, Yongxing, Wang, Quanyi, Zhu, Juanjuan, Wang, Chen, Cui, Shufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093233/
https://www.ncbi.nlm.nih.gov/pubmed/33767433
http://dx.doi.org/10.1038/s41423-021-00668-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093233/
https://www.ncbi.nlm.nih.gov/pubmed/33767433
http://dx.doi.org/10.1038/s41423-021-00668-x

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