Disruption of prepulse inhibition is associated with compulsive behavior severity and nucleus accumbens dopamine receptor changes in Sapap3 knockout mice

Obsessive compulsive disorder (OCD) is associated with disruption of sensorimotor gating, which may contribute to difficulties inhibiting intrusive thoughts and compulsive rituals. Neural mechanisms underlying these disturbances are unclear; however, striatal dopamine is implicated in regulation of...

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Detalles Bibliográficos
Autores principales: Manning, Elizabeth E., Wang, Abigail Y., Saikali, Linda M., Winner, Anna S., Ahmari, Susanne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093235/
https://www.ncbi.nlm.nih.gov/pubmed/33941812
http://dx.doi.org/10.1038/s41598-021-88769-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093235/
https://www.ncbi.nlm.nih.gov/pubmed/33941812
http://dx.doi.org/10.1038/s41598-021-88769-5

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