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Disruption of prepulse inhibition is associated with compulsive behavior severity and nucleus accumbens dopamine receptor changes in Sapap3 knockout mice
Obsessive compulsive disorder (OCD) is associated with disruption of sensorimotor gating, which may contribute to difficulties inhibiting intrusive thoughts and compulsive rituals. Neural mechanisms underlying these disturbances are unclear; however, striatal dopamine is implicated in regulation of...
Autores principales: | Manning, Elizabeth E., Wang, Abigail Y., Saikali, Linda M., Winner, Anna S., Ahmari, Susanne E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093235/ https://www.ncbi.nlm.nih.gov/pubmed/33941812 http://dx.doi.org/10.1038/s41598-021-88769-5 |
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