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High shear resistance of insect cells: the basis for substantial improvements in cell culture process design
Multicellular organisms cultivated in continuous stirred tank reactors (CSTRs) are more sensitive to environmental conditions in the suspension culture than microbial cells. The hypothesis, that stirring induced shear stress is the main problem, persists, although it has been shown that these cells...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093278/ https://www.ncbi.nlm.nih.gov/pubmed/33941799 http://dx.doi.org/10.1038/s41598-021-88813-4 |