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Released Myeloperoxidase Attenuates Neutrophil Migration and Accumulation in Inflamed Tissue

Neutrophil (PMN) recruitment to sites of insult is critical for host defense, however excessive PMN activity and tissue accumulation can lead to exacerbated inflammation and injury. Myeloperoxidase (MPO) is a PMN azurophilic granule enzyme, which together with H(2)O(2), forms a powerful antimicrobia...

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Detalles Bibliográficos
Autores principales: Rehring, Jacob F., Bui, Triet M., Galán-Enríquez, Carlos Samuel, Urbanczyk, Jessica M., Ren, Xingsheng, Wiesolek, Hannah L., Sullivan, David P., Sumagin, Ronen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093447/
https://www.ncbi.nlm.nih.gov/pubmed/33959129
http://dx.doi.org/10.3389/fimmu.2021.654259