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Gastric floating tablet improves the bioavailability and reduces the hypokalemia effect of gossypol in vivo
Gossypol (Gos) is a natural polyphenolic compound that has shown a number of valuable biological properties such as antifertility, antioxidation, and antitumor activities. However, the clinical application of Gos has been hindered by its notable adverse effects such as hypokalemia, hemolytic anemia,...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093546/ https://www.ncbi.nlm.nih.gov/pubmed/33994825 http://dx.doi.org/10.1016/j.jsps.2021.03.001 |