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Enhanced target cell specificity and uptake of lipid nanoparticles using RNA aptamers and peptides

Lipid nanoparticles (LNPs) constitute a facile and scalable approach for delivery of payloads to human cells. LNPs are relatively immunologically inert and can be produced in a cost effective and scalable manner. However, targeting and delivery of LNPs across the blood–brain barrier (BBB) has proven...

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Detalles Bibliográficos
Autores principales: Ray, Roslyn M, Hansen, Anders Højgaard, Taskova, Maria, Jandl, Bernhard, Hansen, Jonas, Soemardy, Citra, Morris, Kevin V, Astakhova, Kira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093553/
https://www.ncbi.nlm.nih.gov/pubmed/33981364
http://dx.doi.org/10.3762/bjoc.17.75