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Beyond ribose and phosphate: Selected nucleic acid modifications for structure–function investigations and therapeutic applications
Over the past 25 years, the acceleration of achievements in the development of oligonucleotide-based therapeutics has resulted in numerous new drugs making it to the market for the treatment of various diseases. Oligonucleotides with alterations to their scaffold, prepared with modified nucleosides...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093555/ https://www.ncbi.nlm.nih.gov/pubmed/33981365 http://dx.doi.org/10.3762/bjoc.17.76 |