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Beyond ribose and phosphate: Selected nucleic acid modifications for structure–function investigations and therapeutic applications

Over the past 25 years, the acceleration of achievements in the development of oligonucleotide-based therapeutics has resulted in numerous new drugs making it to the market for the treatment of various diseases. Oligonucleotides with alterations to their scaffold, prepared with modified nucleosides...

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Detalles Bibliográficos
Autores principales: Liczner, Christopher, Duke, Kieran, Juneau, Gabrielle, Egli, Martin, Wilds, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093555/
https://www.ncbi.nlm.nih.gov/pubmed/33981365
http://dx.doi.org/10.3762/bjoc.17.76