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Development and interpretation of a QSAR model for in vitro breast cancer (MCF-7) cytotoxicity of 2-phenylacrylonitriles

The Arylhydrocarbon Receptor (AhR), a member of the Per-ARNT-SIM transcription factor family, has been as a potential new target to treat breast cancer sufferers. A series of 2-phenylacrylonitriles targeting AhR has been developed that have shown promising and selective activity against cancerous ce...

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Detalles Bibliográficos
Autores principales: Stanton, David T., Baker, Jennifer R., McCluskey, Adam, Paula, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093599/
https://www.ncbi.nlm.nih.gov/pubmed/33945106
http://dx.doi.org/10.1007/s10822-021-00387-5