Rapamycin Promotes ROS-Mediated Cell Death via Functional Inhibition of xCT Expression in Melanoma Under γ-Irradiation

Although many cancer patients are administered radiotherapy for their treatment, the interaction between tumor cells and macrophages in the tumor microenvironment attenuates the curative effects of radiotherapy. The enhanced activation of mTOR signaling in the tumors promotes tumor radioresistance....

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Detalles Bibliográficos
Autores principales: Woo, Yunseo, Lee, Hyo-Ji, Kim, Jeongyeon, Kang, Seung Goo, Moon, Sungjin, Han, Jeong A., Jung, Young Mee, Jung, Yu-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093631/
https://www.ncbi.nlm.nih.gov/pubmed/33959512
http://dx.doi.org/10.3389/fonc.2021.665420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093631/
https://www.ncbi.nlm.nih.gov/pubmed/33959512
http://dx.doi.org/10.3389/fonc.2021.665420

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