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The Association Between Glucocorticoid Administration and the Risk of Impaired Efficacy of Axicabtagene Ciloleucel Treatment: A Systematic Review

BACKGROUND: Glucocorticoid is one of the common and important strategies for the treatment of chimeric antigen receptor T (CAR-T) cell therapy-related toxicity. However, there has been a theoretical concern about whether glucocorticoids use can impact the expansion of CAR-T cells and thus impair its...

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Detalles Bibliográficos
Autores principales: Sun, Zhen, Xun, RenDe, Liu, MengSi, Wu, XiaoQin, Qu, HongTao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093636/
https://www.ncbi.nlm.nih.gov/pubmed/33959128
http://dx.doi.org/10.3389/fimmu.2021.646450