Cyclin G2, a novel target of sulindac to inhibit cell cycle progression in colorectal cancer

Sulindac has shown significant clinical benefit in preventing colorectal cancer progression, but its mechanism of action has not been fully elucidated. We have found that sulindac sulfide (SS) is able to inhibit cell cycle progression in human colorectal cancer cells, particularly through G1 arrest....

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Detalles Bibliográficos
Autores principales: Zhao, Hongyou, Yi, Bin, Liang, Zhipin, Phillips, Ches’Nique, Lin, Hui-Yi, Riker, Adam I., Xi, Yaguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093647/
https://www.ncbi.nlm.nih.gov/pubmed/33997179
http://dx.doi.org/10.1016/j.gendis.2020.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093647/
https://www.ncbi.nlm.nih.gov/pubmed/33997179
http://dx.doi.org/10.1016/j.gendis.2020.11.006

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