THBS1 regulates trophoblast fusion through a CD36-dependent inhibition of cAMP, and its upregulation participates in preeclampsia

Preeclampsia is a pregnancy complication which threatens the survival of mothers and fetuses. It originates from abnormal placentation, especially insufficient fusion of the cytotrophoblast cells to form the syncytiotrophoblast. In this study, we found that THBS1, a matricellular protein that mediat...

Descripción completa

Detalles Bibliográficos
Autores principales: Duan, Fu-Mei, Fu, Li-Juan, Wang, Yong-Heng, Adu-Gyamfi, Enoch Appiah, Ruan, Ling- Ling, Xu, Zeng-Wei, Xiao, Shi-Quan, Chen, Xue-Mei, Wang, Ying-Xiong, Liu, Tai-Hang, Ding, Yu-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093648/
https://www.ncbi.nlm.nih.gov/pubmed/33997182
http://dx.doi.org/10.1016/j.gendis.2020.05.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093648/
https://www.ncbi.nlm.nih.gov/pubmed/33997182
http://dx.doi.org/10.1016/j.gendis.2020.05.007

Ejemplares similares