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Ubiquitin-specific peptidase 18 regulates the differentiation and function of Treg cells

Ubiquitin-specific peptidase 18 (USP18) plays an important role in the development of CD11b(+) dendritic cells (DCs) and Th17 cells, however, its role in the differentiation of other T cell subsets, especially in regulatory T (Treg) cells, is unknown. In our study, we used Usp18 KO mice to study the...

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Detalles Bibliográficos
Autores principales: Yang, Lu, Jing, Yukai, Kang, Danqing, Jiang, Panpan, Li, Na, Zhou, Xinrong, Chen, Yan, Westerberg, Lisa S., Liu, Chaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093650/
https://www.ncbi.nlm.nih.gov/pubmed/33997181
http://dx.doi.org/10.1016/j.gendis.2020.03.004