Common Variants Associated With OSMR Expression Contribute to Carotid Plaque Vulnerability, but Not to Cardiovascular Disease in Humans

Background and Aims: Oncostatin M (OSM) signaling is implicated in atherosclerosis, however the mechanism remains unclear. We investigated the impact of common genetic variants in OSM and its receptors, OSMR and LIFR, on overall plaque vulnerability, plaque phenotype, intraplaque OSMR and LIFR expre...

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Detalles Bibliográficos
Autores principales: van Keulen, Danielle, van Koeverden, Ian D., Boltjes, Arjan, Princen, Hans M. G., van Gool, Alain J., de Borst, Gert J., Asselbergs, Folkert W., Tempel, Dennie, Pasterkamp, Gerard, van der Laan, Sander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093786/
https://www.ncbi.nlm.nih.gov/pubmed/33959646
http://dx.doi.org/10.3389/fcvm.2021.658915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093786/
https://www.ncbi.nlm.nih.gov/pubmed/33959646
http://dx.doi.org/10.3389/fcvm.2021.658915

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