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Xanthohumol ameliorates Diet-Induced Liver Dysfunction via Farnesoid X Receptor-Dependent and Independent Signaling

The farnesoid X receptor (FXR) plays a critical role in the regulation of lipid and bile acid (BA) homeostasis. Hepatic FXR loss results in lipid and BA accumulation, and progression from hepatic steatosis to nonalcoholic steatohepatitis (NASH). This study aimed to evaluate the effects of xanthohumo...

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Detalles Bibliográficos
Autores principales: Paraiso, Ines L., Tran, Thai Q., Magana, Armando Alcazar, Kundu, Payel, Choi, Jaewoo, Maier, Claudia S., Bobe, Gerd, Raber, Jacob, Kioussi, Chrissa, Stevens, Jan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093804/
https://www.ncbi.nlm.nih.gov/pubmed/33959012
http://dx.doi.org/10.3389/fphar.2021.643857