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Xanthohumol ameliorates Diet-Induced Liver Dysfunction via Farnesoid X Receptor-Dependent and Independent Signaling
The farnesoid X receptor (FXR) plays a critical role in the regulation of lipid and bile acid (BA) homeostasis. Hepatic FXR loss results in lipid and BA accumulation, and progression from hepatic steatosis to nonalcoholic steatohepatitis (NASH). This study aimed to evaluate the effects of xanthohumo...
Autores principales: | Paraiso, Ines L., Tran, Thai Q., Magana, Armando Alcazar, Kundu, Payel, Choi, Jaewoo, Maier, Claudia S., Bobe, Gerd, Raber, Jacob, Kioussi, Chrissa, Stevens, Jan F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093804/ https://www.ncbi.nlm.nih.gov/pubmed/33959012 http://dx.doi.org/10.3389/fphar.2021.643857 |
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