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Advances in Genome Editing and Application to the Generation of Genetically Modified Rat Models
The rat has been extensively used as a small animal model. Many genetically engineered rat models have emerged in the last two decades, and the advent of gene-specific nucleases has accelerated their generation in recent years. This review covers the techniques and advances used to generate genetica...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093876/ https://www.ncbi.nlm.nih.gov/pubmed/33959146 http://dx.doi.org/10.3389/fgene.2021.615491 |