Anxiolytic and antidepressant-like effects of essential oil from the fruits of Piper nigrum Linn. (Black pepper) in mice: involvement of serotonergic but not GABAergic transmission system

In this study, the anxiolytic activity of Piper nigrum essential oil (PNEO) was evaluated in the elevated plus maze (EPM) and the antidepressant-like effect was evaluated through tail suspension test (TST) in mice. Flumazenil, a competitive inhibitor of GABA(A) receptor in the benzodiazepine site an...

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Detalles Bibliográficos
Autores principales: Ghosh, Sourav, Kumar, Arvind, Sachan, Neetu, Chandra, Phool
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093886/
https://www.ncbi.nlm.nih.gov/pubmed/33997409
http://dx.doi.org/10.1016/j.heliyon.2021.e06884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093886/
https://www.ncbi.nlm.nih.gov/pubmed/33997409
http://dx.doi.org/10.1016/j.heliyon.2021.e06884

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