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Lin28a ameliorates glucotoxicity-induced β-cell dysfunction and apoptosis
An excessive and prolonged increase in glucose levels causes β-cell dysregulation, which is accompanied by impaired insulin synthesis and secretion, a condition known as glucotoxicity. Although it is known that both Lin28a and Lin28b regulate glucose metabolism, other molecular mechanisms that may p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093937/ https://www.ncbi.nlm.nih.gov/pubmed/33691905 http://dx.doi.org/10.5483/BMBRep.2021.54.4.255 |