Gluconeogenic signals regulate hepcidin gene expression via a CRBN-KLF15 axis

Hepcidin (HAMP) is synthesized in the liver. It is a key iron-regulatory hormone that controls systemic iron homeostasis. Cereblon (CRBN) and Kruppel-like factor 15 (KLF15) are known to regulate diverse physiological functions. In this study, we investigated the role of CRBN on hepatic hepcidin gene...

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Detalles Bibliográficos
Autores principales: Jo, Jeong-Rang, Lee, Sung-Eun, An, Seungwon, Nedumaran, Balachandar, Ghosh, Swati, Park, Keun-Gyu, Kim, Yong Deuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093939/
https://www.ncbi.nlm.nih.gov/pubmed/33795032
http://dx.doi.org/10.5483/BMBRep.2021.54.4.215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093939/
https://www.ncbi.nlm.nih.gov/pubmed/33795032
http://dx.doi.org/10.5483/BMBRep.2021.54.4.215

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