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Gluconeogenic signals regulate hepcidin gene expression via a CRBN-KLF15 axis
Hepcidin (HAMP) is synthesized in the liver. It is a key iron-regulatory hormone that controls systemic iron homeostasis. Cereblon (CRBN) and Kruppel-like factor 15 (KLF15) are known to regulate diverse physiological functions. In this study, we investigated the role of CRBN on hepatic hepcidin gene...
Autores principales: | Jo, Jeong-Rang, Lee, Sung-Eun, An, Seungwon, Nedumaran, Balachandar, Ghosh, Swati, Park, Keun-Gyu, Kim, Yong Deuk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093939/ https://www.ncbi.nlm.nih.gov/pubmed/33795032 http://dx.doi.org/10.5483/BMBRep.2021.54.4.215 |
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