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Bmi1 regulate tooth and mandible development by inhibiting p16 signal pathway
To determine whether the deletion of p16 can correct tooth and mandible growth retardation caused by Bmi1 deficiency, we compared the tooth and mandible phenotypes of homozygous p16‐deficient (p16(−/−)) mice, homozygous Bmi1‐deficient (Bmi1(−/−)) mice, double homozygous Bmi1 and p16‐deficient (Bmi1(...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093977/ https://www.ncbi.nlm.nih.gov/pubmed/33745198 http://dx.doi.org/10.1111/jcmm.16468 |