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Bmi1 regulate tooth and mandible development by inhibiting p16 signal pathway

To determine whether the deletion of p16 can correct tooth and mandible growth retardation caused by Bmi1 deficiency, we compared the tooth and mandible phenotypes of homozygous p16‐deficient (p16(−/−)) mice, homozygous Bmi1‐deficient (Bmi1(−/−)) mice, double homozygous Bmi1 and p16‐deficient (Bmi1(...

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Detalles Bibliográficos
Autores principales: Yin, Ying, Zhou, Nan, Zhang, Hui, Dai, Xiuliang, Lv, Xianhui, Chen, Ning, Miao, Dengshun, Hu, Qingang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093977/
https://www.ncbi.nlm.nih.gov/pubmed/33745198
http://dx.doi.org/10.1111/jcmm.16468