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Dysregulation of LINC00470 and METTL3 promotes chemoresistance and suppresses autophagy of chronic myelocytic leukaemia cells

Cytoplasmic lncRNAs have been found to directly interact with target mRNAs and regulate their stability. In this study, we aimed to study the molecular mechanism underlying the function of m(6)A as a central regulator in chemoresistance and CML proliferation. In this study, we established three mice...

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Detalles Bibliográficos
Autores principales: Lai, Xun, Wei, Jia, Gu, Xue‐zhong, Yao, Xiang‐mei, Zhang, Di‐si, Li, Feng, Sun, Yun‐yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8093980/
https://www.ncbi.nlm.nih.gov/pubmed/33749070
http://dx.doi.org/10.1111/jcmm.16478