Papaverine Exerts Neuroprotective Effect by Inhibiting NLRP3 Inflammasome Activation in an MPTP-Induced Microglial Priming Mouse Model Challenged with LPS

Microglial priming is the process of microglial proliferation and activation in response to neurodegeneration and abnormal protein accumulation. Priming makes microglia susceptible to secondary inflammatory stimuli and causes exaggerated inflammatory responses. In the present study, we established a...

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Detalles Bibliográficos
Autores principales: Leem, Yea-Hyun, Park, Jin-Sun, Park, Jung-Eun, Kim, Do-Yeon, Kim, Hee-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094076/
https://www.ncbi.nlm.nih.gov/pubmed/33911050
http://dx.doi.org/10.4062/biomolther.2021.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094076/
https://www.ncbi.nlm.nih.gov/pubmed/33911050
http://dx.doi.org/10.4062/biomolther.2021.039

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