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Papaverine Exerts Neuroprotective Effect by Inhibiting NLRP3 Inflammasome Activation in an MPTP-Induced Microglial Priming Mouse Model Challenged with LPS
Microglial priming is the process of microglial proliferation and activation in response to neurodegeneration and abnormal protein accumulation. Priming makes microglia susceptible to secondary inflammatory stimuli and causes exaggerated inflammatory responses. In the present study, we established a...
Autores principales: | Leem, Yea-Hyun, Park, Jin-Sun, Park, Jung-Eun, Kim, Do-Yeon, Kim, Hee-Sun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094076/ https://www.ncbi.nlm.nih.gov/pubmed/33911050 http://dx.doi.org/10.4062/biomolther.2021.039 |
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