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Identification of hot regions in hub protein–protein interactions by clustering and PPRA optimization
BACKGROUND: Protein–protein interactions (PPIs) are the core of protein function, which provide an effective means to understand the function at cell level. Identification of PPIs is the crucial foundation of predicting drug-target interactions. Although traditional biological experiments of identif...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094484/ https://www.ncbi.nlm.nih.gov/pubmed/33941163 http://dx.doi.org/10.1186/s12911-020-01350-4 |