Cargando…

Identification of hot regions in hub protein–protein interactions by clustering and PPRA optimization

BACKGROUND: Protein–protein interactions (PPIs) are the core of protein function, which provide an effective means to understand the function at cell level. Identification of PPIs is the crucial foundation of predicting drug-target interactions. Although traditional biological experiments of identif...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Xiaoli, Zhang, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094484/
https://www.ncbi.nlm.nih.gov/pubmed/33941163
http://dx.doi.org/10.1186/s12911-020-01350-4