Multi-tissue neocortical transcriptome-wide association study implicates 8 genes across 6 genomic loci in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is an incurable neurodegenerative disease currently affecting 1.75% of the US population, with projected growth to 3.46% by 2050. Identifying common genetic variants driving differences in transcript expression that confer AD risk is necessary to elucidate AD mec...

Descripción completa

Detalles Bibliográficos
Autores principales: Gockley, Jake, Montgomery, Kelsey S., Poehlman, William L., Wiley, Jesse C., Liu, Yue, Gerasimov, Ekaterina, Greenwood, Anna K., Sieberts, Solveig K., Wingo, Aliza P., Wingo, Thomas S., Mangravite, Lara M., Logsdon, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094491/
https://www.ncbi.nlm.nih.gov/pubmed/33947463
http://dx.doi.org/10.1186/s13073-021-00890-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094491/
https://www.ncbi.nlm.nih.gov/pubmed/33947463
http://dx.doi.org/10.1186/s13073-021-00890-2

Ejemplares similares