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Single-cell sequencing of the small and AT-skewed genome of malaria parasites

Single-cell genomics is a rapidly advancing field; however, most techniques are designed for mammalian cells. We present a single-cell sequencing pipeline for an intracellular parasite, Plasmodium falciparum, with a small genome of extreme base content. Through optimization of a quasi-linear amplifi...

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Detalles Bibliográficos
Autores principales: Liu, Shiwei, Huckaby, Adam C., Brown, Audrey C., Moore, Christopher C., Burbulis, Ian, McConnell, Michael J., Güler, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094492/
https://www.ncbi.nlm.nih.gov/pubmed/33947449
http://dx.doi.org/10.1186/s13073-021-00889-9