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Single-cell sequencing of the small and AT-skewed genome of malaria parasites
Single-cell genomics is a rapidly advancing field; however, most techniques are designed for mammalian cells. We present a single-cell sequencing pipeline for an intracellular parasite, Plasmodium falciparum, with a small genome of extreme base content. Through optimization of a quasi-linear amplifi...
Autores principales: | Liu, Shiwei, Huckaby, Adam C., Brown, Audrey C., Moore, Christopher C., Burbulis, Ian, McConnell, Michael J., Güler, Jennifer L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094492/ https://www.ncbi.nlm.nih.gov/pubmed/33947449 http://dx.doi.org/10.1186/s13073-021-00889-9 |
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