Identification and characterization of a G-quadruplex structure in the pre-core promoter region of hepatitis B virus covalently closed circular DNA

Approximately 250 million people worldwide are chronically infected with the hepatitis B virus (HBV) and are at increased risk of developing cirrhosis and hepatocellular carcinoma. The HBV genome persists as covalently closed circular DNA (cccDNA), which serves as the template for all HBV mRNA trans...

Descripción completa

Detalles Bibliográficos
Autores principales: Meier-Stephenson, Vanessa, Badmalia, Maulik D., Mrozowich, Tyler, Lau, Keith C.K., Schultz, Sarah K., Gemmill, Darren L., Osiowy, Carla, van Marle, Guido, Coffin, Carla S., Patel, Trushar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094906/
https://www.ncbi.nlm.nih.gov/pubmed/33774051
http://dx.doi.org/10.1016/j.jbc.2021.100589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094906/
https://www.ncbi.nlm.nih.gov/pubmed/33774051
http://dx.doi.org/10.1016/j.jbc.2021.100589

Ejemplares similares