Cargando…

Sequence Evaluation and Comparative Analysis of Novel Assays for Intact Proviral HIV-1 DNA

The HIV proviral reservoir is the major barrier to cure. The predominantly replication-defective proviral landscape makes the measurement of virus that is likely to cause rebound upon antiretroviral therapy (ART)-cessation challenging. To address this issue, novel assays to measure intact HIV provir...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaebler, Christian, Falcinelli, Shane D., Stoffel, Elina, Read, Jenna, Murtagh, Ross, Oliveira, Thiago Y., Ramos, Victor, Lorenzi, Julio C. C., Kirchherr, Jennifer, James, Katherine S., Allard, Brigitte, Baker, Caroline, Kuruc, JoAnn D., Caskey, Marina, Archin, Nancie M., Siliciano, Robert F., Margolis, David M., Nussenzweig, Michel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094944/
https://www.ncbi.nlm.nih.gov/pubmed/33361426
http://dx.doi.org/10.1128/JVI.01986-20