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Sequence Evaluation and Comparative Analysis of Novel Assays for Intact Proviral HIV-1 DNA
The HIV proviral reservoir is the major barrier to cure. The predominantly replication-defective proviral landscape makes the measurement of virus that is likely to cause rebound upon antiretroviral therapy (ART)-cessation challenging. To address this issue, novel assays to measure intact HIV provir...
Autores principales: | Gaebler, Christian, Falcinelli, Shane D., Stoffel, Elina, Read, Jenna, Murtagh, Ross, Oliveira, Thiago Y., Ramos, Victor, Lorenzi, Julio C. C., Kirchherr, Jennifer, James, Katherine S., Allard, Brigitte, Baker, Caroline, Kuruc, JoAnn D., Caskey, Marina, Archin, Nancie M., Siliciano, Robert F., Margolis, David M., Nussenzweig, Michel C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094944/ https://www.ncbi.nlm.nih.gov/pubmed/33361426 http://dx.doi.org/10.1128/JVI.01986-20 |
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