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miR-21-5p targets SKP2 to reduce osteoclastogenesis in a mouse model of osteoporosis

Osteoporosis results from an imbalance between bone formation and bone resorption. Traditional drugs for treating osteoporosis are associated with serious side effects, and thus, new treatment methods are required. This study investigated the role of differentially expressed microRNAs during osteocl...

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Detalles Bibliográficos
Autores principales: Huang, Yizhen, Yang, Yute, Wang, Jianle, Yao, Shasha, Yao, Teng, Xu, Yining, Chen, Zizheng, Yuan, Putao, Gao, Jun, Shen, Shuying, Ma, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095171/
https://www.ncbi.nlm.nih.gov/pubmed/33811860
http://dx.doi.org/10.1016/j.jbc.2021.100617