Improving therapeutic potential of non-viral minimized DNA vectors

The tragic deaths of three patients in a recent AAV-based X-linked myotubular myopathy clinical trial highlight once again the pressing need for safe and reliable gene delivery vectors. Non-viral minimized DNA vectors offer one possible way to meet this need. Recent pre-clinical results with minimiz...

Descripción completa

Detalles Bibliográficos
Autores principales: Arévalo-Soliz, Lirio M, Hardee, Cinnamon L, Fogg, Jonathan M, Corman, Nathan R, Noorbakhsh, Cameron, Zechiedrich, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095377/
https://www.ncbi.nlm.nih.gov/pubmed/33953961
http://dx.doi.org/10.18609/cgti.2020.163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095377/
https://www.ncbi.nlm.nih.gov/pubmed/33953961
http://dx.doi.org/10.18609/cgti.2020.163

Ejemplares similares