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F-Box Protein FBXW17-Mediated Proteasomal Degradation of Protein Methyltransferase PRMT6 Exaggerates CSE-Induced Lung Epithelial Inflammation and Apoptosis

Chronic obstructive pulmonary disease (COPD) is a chronic debilitating lung disease, characterized by progressive airway inflammation and lung structural cell death. Cigarette smoke is considered the most common risk factor of COPD pathogenesis. Understanding the molecular mechanisms of persistent i...

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Detalles Bibliográficos
Autores principales: Li, Tiao, He, Xue, Luo, Lijuan, Zeng, Huihui, Ren, Siying, Chen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095709/
https://www.ncbi.nlm.nih.gov/pubmed/33959602
http://dx.doi.org/10.3389/fcell.2021.599020