Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice

Many neurodevelopmental disorders are characterized by impaired functional synaptic plasticity and abnormal dendritic spine morphology, but little is known about how these are related. Previous work in the Fmr1(-/y) mouse model of fragile X (FX) suggests that increased constitutive dendritic protein...

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Detalles Bibliográficos
Autores principales: Thomazeau, Aurore, Bosch, Miquel, Essayan-Perez, Sofia, Barnes, Stephanie A., De Jesus-Cortes, Hector, Bear, Mark F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095717/
https://www.ncbi.nlm.nih.gov/pubmed/32606374
http://dx.doi.org/10.1038/s41380-020-0821-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095717/
https://www.ncbi.nlm.nih.gov/pubmed/32606374
http://dx.doi.org/10.1038/s41380-020-0821-6

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