Empagliflozin ameliorates symptoms of diabetes and renal tubular dysfunction in a rat model of diabetes with enlarged kidney (DEK)

BACKGROUND: Sodium-glucose cotransporter 2 (SGLT2) inhibitors are widely used to reduce hyperglycemia. The present study investigated the effects of a SGLT2 inhibitor, empagliflozin, on hyperglycemia in a novel rat model of non-obesity type 2 diabetes with enlarged kidney (DEK). METHODS: Male DEK ra...

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Detalles Bibliográficos
Autores principales: Domon, Ayaka, Katayama, Kentaro, Sato, Touko, Tochigi, Yuki, Tazaki, Hiroyuki, Suzuki, Hiroetsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096081/
https://www.ncbi.nlm.nih.gov/pubmed/33945582
http://dx.doi.org/10.1371/journal.pone.0251135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096081/
https://www.ncbi.nlm.nih.gov/pubmed/33945582
http://dx.doi.org/10.1371/journal.pone.0251135

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