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The SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the ongoing coronavirus disease 2019 pandemic. How SARS-CoV-2 regulates cellular responses to escape clearance by host cells is unknown. Autophagy is an intracellular lysosomal degradation pathway for the clearance of various ca...

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Detalles Bibliográficos
Autores principales: Zhang, Yabin, Sun, Hao, Pei, Rongjuan, Mao, Binli, Zhao, Zhenyu, Li, Huihui, Lin, Yong, Lu, Kefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096138/
https://www.ncbi.nlm.nih.gov/pubmed/33947832
http://dx.doi.org/10.1038/s41421-021-00268-z