The rDNA is biomolecular condensate formed by polymer–polymer phase separation and is sequestered in the nucleolus by transcription and R-loops

The nucleolus is the site of ribosome biosynthesis encompassing the ribosomal DNA (rDNA) locus in a phase separated state within the nucleus. In budding yeast, we find the rDNA locus and Cdc14, a protein phosphatase that co-localizes with the rDNA, behave like a condensate formed by polymer–polymer...

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Detalles Bibliográficos
Autores principales: Lawrimore, Josh, Kolbin, Daniel, Stanton, John, Khan, Muznah, de Larminat, Solenn C, Lawrimore, Colleen, Yeh, Elaine, Bloom, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096216/
https://www.ncbi.nlm.nih.gov/pubmed/33836082
http://dx.doi.org/10.1093/nar/gkab229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096216/
https://www.ncbi.nlm.nih.gov/pubmed/33836082
http://dx.doi.org/10.1093/nar/gkab229

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