DNA polymerase D temporarily connects primase to the CMG-like helicase before interacting with proliferating cell nuclear antigen

The eukaryotic replisome is comprised of three family-B DNA polymerases (Polα, δ and ϵ). Polα forms a stable complex with primase to synthesize short RNA-DNA primers, which are subsequently elongated by Polδ and Polϵ in concert with proliferating cell nuclear antigen (PCNA). In some species of archa...

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Detalles Bibliográficos
Autores principales: Oki, Keisuke, Yamagami, Takeshi, Nagata, Mariko, Mayanagi, Kouta, Shirai, Tsuyoshi, Adachi, Naruhiko, Numata, Tomoyuki, Ishino, Sonoko, Ishino, Yoshizumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096248/
https://www.ncbi.nlm.nih.gov/pubmed/33849056
http://dx.doi.org/10.1093/nar/gkab243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096248/
https://www.ncbi.nlm.nih.gov/pubmed/33849056
http://dx.doi.org/10.1093/nar/gkab243

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