Analysis of the tumor microenvironment and anti-tumor efficacy of subcutaneous vs systemic delivery of the bifunctional agent bintrafusp alfa

Most monoclonal antibodies (MAbs), including immune checkpoint inhibitor MAbs, are delivered intravenously (i.v.) to patients. Recent clinical studies have demonstrated that some anti-PD1 MAbs may also be delivered subcutaneously (s.c.), with clinical outcomes similar of those obtained with i.v.-del...

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Detalles Bibliográficos
Autores principales: Ozawa, Yohei, Hicks, Kristin C., Minnar, Christine M., Knudson, Karin M., Schlom, Jeffrey, Gameiro, Sofia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096334/
https://www.ncbi.nlm.nih.gov/pubmed/33996267
http://dx.doi.org/10.1080/2162402X.2021.1915561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096334/
https://www.ncbi.nlm.nih.gov/pubmed/33996267
http://dx.doi.org/10.1080/2162402X.2021.1915561

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