APOE and Alzheimer’s Disease: Advances in Genetics, Pathophysiology, and Therapeutic Approaches.

The APOE ε4 allele remains the strongest genetic risk factor for sporadic Alzheimer’s disease and the APOE ε2 allele the strongest genetic protective factor after multiple large scale genome-wide association studies and genome-wide association meta-analyses. However, no therapies directed at APOE ar...

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Detalles Bibliográficos
Autores principales: Serrano-Pozo, Alberto, Das, Sudeshna, Hyman, Bradley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096522/
https://www.ncbi.nlm.nih.gov/pubmed/33340485
http://dx.doi.org/10.1016/S1474-4422(20)30412-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096522/
https://www.ncbi.nlm.nih.gov/pubmed/33340485
http://dx.doi.org/10.1016/S1474-4422(20)30412-9

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