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Sustained absorption of delamanid from lipid-based formulations as a path to reduced frequency of administration

Delamanid is a poorly water-soluble drug currently being used for the treatment of tuberculosis. The high frequency of dosing leads to poor adherence for patients who live in lower economic and nomadic populations. Non-digestible self-assembling lipids as a formulation approach for poorly water-solu...

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Detalles Bibliográficos
Autores principales: Ramirez, Gisela, Pham, Anna C., Clulow, Andrew J., Salim, Malinda, Hawley, Adrian, Boyd, Ben J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096769/
https://www.ncbi.nlm.nih.gov/pubmed/32935235
http://dx.doi.org/10.1007/s13346-020-00851-z