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Sustained absorption of delamanid from lipid-based formulations as a path to reduced frequency of administration
Delamanid is a poorly water-soluble drug currently being used for the treatment of tuberculosis. The high frequency of dosing leads to poor adherence for patients who live in lower economic and nomadic populations. Non-digestible self-assembling lipids as a formulation approach for poorly water-solu...
Autores principales: | Ramirez, Gisela, Pham, Anna C., Clulow, Andrew J., Salim, Malinda, Hawley, Adrian, Boyd, Ben J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096769/ https://www.ncbi.nlm.nih.gov/pubmed/32935235 http://dx.doi.org/10.1007/s13346-020-00851-z |
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