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Gain and loss of function mutations in biological chemical reaction networks: a mathematical model with application to colorectal cancer cells

This paper studies a system of Ordinary Differential Equations modeling a chemical reaction network and derives from it a simulation tool mimicking Loss of Function and Gain of Function mutations found in cancer cells. More specifically, from a theoretical perspective, our approach focuses on the de...

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Detalles Bibliográficos
Autores principales: Sommariva, Sara, Caviglia, Giacomo, Piana, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096774/
https://www.ncbi.nlm.nih.gov/pubmed/33945019
http://dx.doi.org/10.1007/s00285-021-01607-0