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Gain and loss of function mutations in biological chemical reaction networks: a mathematical model with application to colorectal cancer cells
This paper studies a system of Ordinary Differential Equations modeling a chemical reaction network and derives from it a simulation tool mimicking Loss of Function and Gain of Function mutations found in cancer cells. More specifically, from a theoretical perspective, our approach focuses on the de...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096774/ https://www.ncbi.nlm.nih.gov/pubmed/33945019 http://dx.doi.org/10.1007/s00285-021-01607-0 |