Mitochondrial STAT3 regulates antioxidant gene expression through complex I‐derived NAD in triple negative breast cancer

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor with roles in inflammation and tumorigenicity. A fraction of STAT3 localizes in mitochondria, where it augments tumorigenesis via regulation of mitochondrial functions, including modulation of respiration and redox...

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Detalles Bibliográficos
Autores principales: Lahiri, Tanaya, Brambilla, Lara, Andrade, Joshua, Askenazi, Manor, Ueberheide, Beatrix, Levy, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096790/
https://www.ncbi.nlm.nih.gov/pubmed/33605027
http://dx.doi.org/10.1002/1878-0261.12928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8096790/
https://www.ncbi.nlm.nih.gov/pubmed/33605027
http://dx.doi.org/10.1002/1878-0261.12928

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